HOW IS FRAGILE X SYNDROME INHERITED?

The gene for Fragile X syndrome carried on the X chromosome. Because both males (XY) and females (XX) have at least one X chromosome, both can pass on the mutated gene to their children.

If the mother has the altered gene for Fragile X she can pass that gene to either her sons or her daughters

If the mother has the mutated gene on one chromosome and has one normal X chromosome, and the father has no genetic mutations, all the children have a 50-50 change of inheriting the mutated gene.


TREATMENT OF FRAGILEX SYNDROME


Standart treatment includes specialeducation, speech, occupational, and sensory integration traning; and behavior modification program

DIAGNOSIS OF FRAGILE X SYNDROME

Fragile X syndrome was originally diagnosis by cultıring cells in a folete deficient medium and then assessing the cultures for X chromosome breakage by cytogenetic analysis of the long arm of the X chromosome also diagnosisFragile X syndrome is difficult to diagnose in children.

An affected infant may develop normally at first. After age one year, though, the child begins to have noticeable delays in language and short-term memory. Physical signs of Fragile X, such as the typical facial features, are only noticeable after the onset of puberty.

A blood test known as FMR1/DNA is used to confirm the diagnosis.

SYMPTOMS OF FRAGILE X SYNDROME

Some symptoms of fragile x syndrome below:
Larger ears
Large testes (macroorchidism)
Large jaw (prognathism)
The face is long and narrow
Speech delays
Prominent forehead

WHAT IS FRAGILE X SYNDROME?

Fragile X syndrome is the must common inherited from of mental retardation
It results from a chamge or mutation in a single gene
Symptoms of Fragile X syndrome occur because the mutated gene cannot produce enough of a protein that is needed by the body cell especially in the brain, to developed and normally.
This syndrome is the second most common identifiable cause of genetic mental retardation after Down syndrome

CONTENT OF THIS BLOG

What is Fragile X syndrome?
Symptoms of Fragile X syndrome
Diagnosis of Fragile X syndrome
Treatment of Fragile X syndrome
How is Fragile X syndrome inherited?

CONTENT OF THIS BLOG

What is Fragile X syndrome?
Symptoms of Fragile X syndrome
Diagnosis OF This syndrome
Treatment of Fragile X syndrome
How is Fragile X syndrome inherited?

information about this syndrome ,